Results were published in the peer-reviewed journal, International Urology and Nephrology. Lipella has received FDA Orphan Designation for this product.

HC is serious, life-threatening bladder damage from pelvic radiation therapy and/or bladder-toxic chemotherapy. It causes chronic, painful urinary inflammation and blood loss called hemorrhagic cystitis. The blood loss, associated with hemorrhagic cystitis and radiation cystitis can lead to surgery, and can be fatal. There is currently no FDA approved drug treatment for HC.